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We always go with the flow!

We provide flow cytometry testing services in support of clinical trials, nonclinical studies, toxicology assessments, research and development and the evaluation of flow cytometric products.

We pride ourselves on the ability to customize any flow cytometry assay to meet our client's needs. We also have extensive experience in data collection and analysis utilizing both straight-forward and complex gating strategies.

While we specialize in assay development and customization, we also welcome routine flow cytometry projects such as standard surface immunophenotyping.

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News and Information

  • Latest News
  • Upcoming Events
  • Company Literature
  • AAPS Flow Cytometry APC
  • Job Openings
About FCS Laboratory

About FCS Laboratory

  • About Us
  • Leadership
  • Specialized Service
  • Specimen Shipping
  • Contact Us
Services

Our Flow Cytometry Services

  • Immunophenotyping
  • Bead-Based Methods
  • Cell Signaling
  • Cellular Functional Assays
  • Consulting Services

FCS image

We always go with the flow!

We provide flow cytometry testing services in support of clinical trials, nonclinical studies, toxicology assessments, research and development and the evaluation of flow cytometric products.

We pride ourselves on the ability to customize any flow cytometry assay to meet our client's needs. We also have extensive experience in data collection and analysis utilizing both straight-forward and complex gating strategies.

While we specialize in assay development and customization, we also welcome routine flow cytometry projects such as standard surface immunophenotyping.

Artwork by Abu Atienza and Logo by Christian Tan.

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Latest News

Our flow cytometry services are now featured on Biocompare under both flow cytometry and immunoassay services.

We are pleased to announce that FCSL was selected as the supplier spotlight on Scientist.com. Check out the blog post featuring our company!

The Special Issue dedictated to Receptor Occupancy in Cytometry Part B: Cinical Cytometry was published in March 2016 with open access for a limited time. Jennifer Stewart served as a guest editor and authored the introduction to the special issue and two review articles in the issue.

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Relevant upcoming scheduled events (meetings, conferences, seminars, symposia, etc.):

Event/Conference Date Location
SOT Annual Meeting and Tox Expo Mar 12-16th, 2017 Baltimore, MD
AAPS National Biotechnology Conference May 1- 3rd, 2017 San Diego, CA
ISAC CYTO 2017 Jun 10-14th, 2017 Boston, MA
Annual Clinical Cytometry Meeting Oct 6-10th, 2017 Phoenix, AZ
American College of Toxicology Meeting Nov 5-8th, 2017 Palm Springs, CA
AAPS Annual Meeting Nov 12-15th, 2017 San Diego, CA

If you are interested in scheduling a time to meet with a FCS Laboratory representative to learn more about our services and capabilities or to discuss how we can assist you with your nonclinical and clinical flow cytometry needs, please contact us at (425) 821-3900 or email: info@fcslaboratory.com.

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Our Mission

"We collaborate with our clients, respond to their needs, anticipate regulatory change, invest in our facilities and our people and maintain ourselves at the forefront of flow cytometry."

Our Vision

"Just name it, we can do it!"

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Literature

For more information please see the resources listed below:

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Current Job Openings

FCS Laboratory is building a team of high-caliber scientists who believe in the potential of very specialized testing. We are still a small start-up where individual contributions are highly valued and recognized. In our fast-paced environment, we are helping our clients develop life-changing products and therapies.

    We are currently not hiring for any positions. Please check back in the future as this may change from time to time.

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Brochures and Flyers

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The Marker Archive

  • 2010
  • 2011
  • 2012
  • 2013
  • 2014
  • 2015
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    The Marker Archive

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    The Marker Archive

    • Issue 14, First and Second Quarter 2014
    • Issue 15, Third Quarter 2014
    • Issue 16, Fourth Quarter 2014
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      entrance

      The Marker Archive

      • Issue 17, Summer 2015
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        news

        Flow Cytometry Action Programming Committee

        The Flow Cytometry APC is a subgroup of the AAPS LBABFG. We are proud members of this collaboration of experts whose main goal is to establish recommendations, guidelines and criteria for using flow cytometry assays and instrumentation during drug development.

        Please visit the interactive LinkedIn Group "Flow Cytometry Action Program Committee" for more information or to join.

        We are proud to be presenting two worshops at the upcoming ISAC CYTO2017 meeting! Please see Workshop 6 and Workshop 18 for more information. We hope to see many of you in Boston in June!

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        About Us

          Founded in 2009, FCS Laboratory specializes in flow cytometry services for drug development. We provide:

        • First rate and personal customer service with frequent project updates
        • State of the art facilities and equipment
        • Prompt, clear, comprehensive, and accurate reporting
        • Turn-around time unequaled by other contract laboratories
        • Up front itemized pricing with no hidden costs
        • Expertise in client processes, eliminating turnover issues
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        The FCS Laboratory Story

        Contact FCS Laboratory

        FCS Laboratory is located in the Canyon Creek Business Center in Bothell, WA (approximately 30 min northeast of Seattle).

        Flow Contract Site Laboratory, LLC

        18311 Bothell Everett Highway, Suite 180

        Bothell, WA 98012

        Phone: (425) 892-2609

        FAX: (425) 408-0583

        Email: info@fcslaboratory.com

        To join our mailing list please email marker@fcslaboratory.com.

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        Leadership

        The owners have combined experience of 20+ years in flow cytometry and 15+ years working in a Good Laboratory Practice (GLP) environment.

        The Management Team

        Lynette Brown, President and Flow Cytometry Specialist

        Jennifer J. Stewart, Vice President and Laboratory Director

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        lynette brown

        Lynette Brown, MS, CHT

        Lynette has 10 years professional experience in flow cytometry both in the clinical and research settings. Lynette has experience with many specimen types including whole blood and tissue from rodents, dogs, non-human primates and humans. She has developed and validated numerous assays for surface and intracellular markers and NK cell function that have been used on more than 50 GLP studies.

        Lynette is in charge of the day to day operation of the laboratory which includes training, instrument maintenance and validation, specimen handling, sample acquisition and data analysis.

        View Lynette Brown's profile on LinkedIn

        jennifer stewart

        Jennifer J Stewart, PhD

        Dr. Stewart has over 20 years professional experience and is responsible for overseeing internal and client sponsored research, preclinical or clinical drug studies using human specimens, non-human primate, dog or rodent models. She scientifically reviews the documentation, analyzes and reports flow cytometry data and communicates directly with Study Directors, Study Monitors and Clients.

        Dr. Stewart is currently serving as a guest editor for Cytometry Part B: Clinical Cytometry and she is a scientific reviewer for the Journal of Immunological Methods and Clinical and Vaccine Immunology.

        View Jennifer J. Stewart, PhD's profile on LinkedIn

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        Specialized Service

        By focusing on flow cytometry services, FCS Laboratory is able to ensure that there is no dilution of the scientific and managerial focus because of unrelated upstream and downstream functions.

        We utilize Becton Dickinson flow cytometers. Currently our facility houses three BD FACSCantoII cytometers with two scatter parameters and up to 8 flourescent channels and a BD FACSCantoA cytometer with two scatter parameters and up to 6 flourescent channels. We also have two Guava PCAs which perform all of our cell count and viability assessments.

        We are proficient in processing a multitude of specimen types including whole blood, tissue, frozen PBMCs and tumors for pre-clinical model systems and human clinical trials.

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        Specimen Shipping

        FCS Laboratory operates as an outsourcing CRO in which specimens are shipped to us for analysis. This provides our clients more flexibility in choosing a laboratory and can reduce overload of their internal resources.

        Since we rely on shipped specimens, we conduct rigorous qualification and validation of our assays to ensure specimen stability is well understood. We will work closely with you to determine appropriate sample preparation and shipping requirements for a particular assay.

        Please see our poster showing the stability of surface, activation and intracellular markers on shipped specimens under US domestic and international shipping time frames.

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        Immunophenotyping

        We use BD FACSCantoTM technology to analyze up to 8-color antibody panels. Our instruments are validated to meet GLP and 21 CFR Part 11 compliance.

          Please see our flyer for more detailed information on our antibody panels.

        • T, B and NK cell enumeration
        • T-lymphocytes and subsets, B-lymphocytes and subsets
        • Monocytes, Granulocytes and Dendritic Cells
        • Receptor Occupancy Assays
        • Custom Panels also available, please inquire!
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        Bead-Based Methods

        We utilize commercially available bead sets to evaluate the following:

        • Excreted cytokines with the BDTM Cytometric Bead Array (CBA) Kits and the Ebiosciences FlowCytomixTM Multiple Analyte Detection System
        • Enrichment of cell populations of interest using STEMCELL Technologies EasySep® and Miltenyi MACS® Separators
        • Enumeration of absolute lymphocyte counts using counting particles. Please see our poster for more info.
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        Cell Signaling

        We are proud to offer flow cytometry assays for elucidation of signal transduction pathways.

          Please see our flyer for more detailed information on our intracellular markers and stains.

        • Intracellular protein staining of cytokines and transcription factors
        • Detection of key protein activation states and cross-talk using phospho-specific antibodies
        • Measurements of DNA content, Cell Cycle Progression and Apoptosis
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        Cellular Functional Assays

        We have full service cell culture capabilities to demonstrate whether or not a cell has the capacity of performing certain functions.

        • Cell count and viability measurements by Guava® PCATM technology
        • Cell Proliferation Assay
        • CTL Assay
        • Natural Killer (NK) Cell Activity, please see our poster for more information on correlation of surface biomarker expression with NK Cell killing
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        Consulting Services

        In addition to our full service flow cytometry offerings, we are pleased to add the following consulting services.

        • Support flow cytometry laboratory set-up and operations
        • Assist with assay development and troubleshooting
        • Facilitate assay transfer from originating laboratory to the site of testing
        • Oversee flow cytometry portions of projects or studies on a global scale
        • Analysis of existing FCS files
        • Data interpretation and reporting
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        We want to hear from you!

        Please direct inquiries and/or questions to info@fcslaboratory.com. To help us respond to your request, please enter your name, email address, phone number, company name and a brief description of your flow cytometry needs and a representative from FCS Laboratory will respond to you shortly.

        For a faster response and to speak directly to a flow cytometry expert, do not hesitate to call us at (425) 821-3900.

        Thank you for your interest in FCS Laboratory!

        To join our mailing list and receive our quarterly updates, please email marker@fcslaboratory.com.

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